PDB 5laz

PDB Links
Overview

PDB Information

PDB	5LAZ
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction. Gollner, A., Rudolph, D., Arnhof, H., Bauer, M., Blake, S.M., Boehmelt, G., Cockroft, X.L., Dahmann, G., Ettmayer, P., Gerstberger, T., Karolyi-Oezguer, J., Kessler, D., Kofink, C., Ramharter, J., Rinnenthal, J., Savchenko, A., Schnitzer, R., Weinstabl, H., Weyer-Czernilofsky, U., Wunberg, T., McConnell, D.B. J. Med. Chem.
Header	Ligase
Released	2016-06-15
Resolution	1.660
CATH Insert Date	20 Nov, 2016

PDB Images (3)

Image of CATH 5laz

5laz

PDB 5laz

Image of CATH 5lazA

5lazA

PDB Chain 5lazA

Image of CATH 5lazA00

5lazA00

CATH Domain 5lazA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	21 Nov, 2016	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5lazA00	25 Nov, 2016	1.10.245.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2