PDB 5laz

PDB Information

PDB5LAZ
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction.
Gollner, A., Rudolph, D., Arnhof, H., Bauer, M., Blake, S.M., Boehmelt, G., Cockroft, X.L., Dahmann, G., Ettmayer, P., Gerstberger, T., Karolyi-Oezguer, J., Kessler, D., Kofink, C., Ramharter, J., Rinnenthal, J., Savchenko, A., Schnitzer, R., Weinstabl, H., Weyer-Czernilofsky, U., Wunberg, T., McConnell, D.B.
J. Med. Chem.
HeaderLigase
Released2016-06-15
Resolution1.660
CATH Insert Date20 Nov, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5lazA00 25 Nov, 2016 1.10.245.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
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