PDB 5law

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Overview

PDB Information

PDB	5LAW
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction. Gollner, A., Rudolph, D., Arnhof, H., Bauer, M., Blake, S.M., Boehmelt, G., Cockroft, X.L., Dahmann, G., Ettmayer, P., Gerstberger, T., Karolyi-Oezguer, J., Kessler, D., Kofink, C., Ramharter, J., Rinnenthal, J., Savchenko, A., Schnitzer, R., Weinstabl, H., Weyer-Czernilofsky, U., Wunberg, T., McConnell, D.B. J. Med. Chem.
Header	Ligase
Released	2016-06-15
Resolution	1.640
CATH Insert Date	20 Nov, 2016

PDB Images (3)

Image of CATH 5law

5law

PDB 5law

Image of CATH 5lawA

5lawA

PDB Chain 5lawA

Image of CATH 5lawA00

5lawA00

CATH Domain 5lawA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	21 Nov, 2016	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5lawA00	25 Nov, 2016	1.10.245.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2