PDB Information

PDB5L64
MethodX-RAY DIFFRACTION
Host OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Gene SourceHomo sapiens
Primary Citation
A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
Huber, E.M., Heinemeyer, W., de Bruin, G., Overkleeft, H.S., Groll, M.
EMBO J.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-05-28
Resolution2.700
CATH Insert Date27 Nov, 2016

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
a 28 Nov, 2016 Chopped
A 28 Nov, 2016 Chopped
b 28 Nov, 2016 Chopped
B 28 Nov, 2016 Chopped
C 28 Nov, 2016 Chopped
D 28 Nov, 2016 Chopped
E 28 Nov, 2016 Chopped
F 28 Nov, 2016 Chopped
G 28 Nov, 2016 Chopped
H 28 Nov, 2016 Chopped
I 28 Nov, 2016 Chopped
J 28 Nov, 2016 Chopped
K 28 Nov, 2016 Chopped
L 28 Nov, 2016 Chopped
M 28 Nov, 2016 Chopped
N 28 Nov, 2016 Chopped
O 28 Nov, 2016 Chopped
P 28 Nov, 2016 Chopped
Q 28 Nov, 2016 Chopped
R 28 Nov, 2016 Chopped
S 28 Nov, 2016 Chopped
T 28 Nov, 2016 Chopped
U 28 Nov, 2016 Chopped
V 28 Nov, 2016 Chopped
W 28 Nov, 2016 Chopped
X 28 Nov, 2016 Chopped
Y 28 Nov, 2016 Chopped
Z 28 Nov, 2016 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
5l64a00 02 Dec, 2016 3.60.20.10 Assigned
5l64A00 02 Dec, 2016 3.60.20.10 Assigned
5l64b00 02 Dec, 2016 3.60.20.10 Assigned
5l64B00 01 Dec, 2016 3.60.20.10 Assigned
5l64C00 02 Dec, 2016 3.60.20.10 Assigned
5l64D00 02 Dec, 2016 3.60.20.10 Assigned
5l64E00 02 Dec, 2016 3.60.20.10 Assigned
5l64F00 01 Dec, 2016 3.60.20.10 Assigned
5l64G00 02 Dec, 2016 3.60.20.10 Assigned
5l64H00 02 Dec, 2016 3.60.20.10 Assigned
5l64I00 02 Dec, 2016 3.60.20.10 Assigned
5l64J00 02 Dec, 2016 3.60.20.10 Assigned
5l64K00 02 Dec, 2016 3.60.20.10 Assigned
5l64L00 01 Dec, 2016 3.60.20.10 Assigned
5l64M00 02 Dec, 2016 3.60.20.10 Assigned
5l64N00 02 Dec, 2016 3.60.20.10 Assigned
5l64O00 02 Dec, 2016 3.60.20.10 Assigned
5l64P00 02 Dec, 2016 3.60.20.10 Assigned
5l64Q00 01 Dec, 2016 3.60.20.10 Assigned
5l64R00 01 Dec, 2016 3.60.20.10 Assigned
5l64S00 01 Dec, 2016 3.60.20.10 Assigned
5l64T00 02 Dec, 2016 3.60.20.10 Assigned
5l64U00 02 Dec, 2016 3.60.20.10 Assigned
5l64V00 01 Dec, 2016 3.60.20.10 Assigned
5l64W00 01 Dec, 2016 3.60.20.10 Assigned
5l64X00 01 Dec, 2016 3.60.20.10 Assigned
5l64Y00 01 Dec, 2016 3.60.20.10 Assigned
5l64Z00 02 Dec, 2016 3.60.20.10 Assigned

UniProtKB Entries (32)

Accession Gene ID Taxon Description
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P28074 PSB5_HUMAN Homo sapiens Proteasome subunit beta type-5
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P28074 PSB5_HUMAN Homo sapiens Proteasome subunit beta type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7