PDB Information

PDB5L5W
MethodX-RAY DIFFRACTION
Host OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Gene SourceHomo sapiens
Primary Citation
A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
Huber, E.M., Heinemeyer, W., de Bruin, G., Overkleeft, H.S., Groll, M.
EMBO J.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-05-28
Resolution2.800
CATH Insert Date20 Nov, 2016

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
a 21 Nov, 2016 Chopped
A 21 Nov, 2016 Chopped
b 21 Nov, 2016 Chopped
B 21 Nov, 2016 Chopped
C 21 Nov, 2016 Chopped
D 21 Nov, 2016 Chopped
E 21 Nov, 2016 Chopped
F 21 Nov, 2016 Chopped
G 21 Nov, 2016 Chopped
H 21 Nov, 2016 Chopped
I 21 Nov, 2016 Chopped
J 21 Nov, 2016 Chopped
K 21 Nov, 2016 Chopped
L 21 Nov, 2016 Chopped
M 21 Nov, 2016 Chopped
N 21 Nov, 2016 Chopped
O 21 Nov, 2016 Chopped
P 21 Nov, 2016 Chopped
Q 21 Nov, 2016 Chopped
R 21 Nov, 2016 Chopped
S 21 Nov, 2016 Chopped
T 21 Nov, 2016 Chopped
U 21 Nov, 2016 Chopped
V 21 Nov, 2016 Chopped
W 21 Nov, 2016 Chopped
X 21 Nov, 2016 Chopped
Y 21 Nov, 2016 Chopped
Z 21 Nov, 2016 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
5l5wa00 25 Nov, 2016 3.60.20.10 Assigned
5l5wA00 25 Nov, 2016 3.60.20.10 Assigned
5l5wb00 25 Nov, 2016 3.60.20.10 Assigned
5l5wB00 25 Nov, 2016 3.60.20.10 Assigned
5l5wC00 25 Nov, 2016 3.60.20.10 Assigned
5l5wD00 25 Nov, 2016 3.60.20.10 Assigned
5l5wE00 25 Nov, 2016 3.60.20.10 Assigned
5l5wF00 25 Nov, 2016 3.60.20.10 Assigned
5l5wG00 25 Nov, 2016 3.60.20.10 Assigned
5l5wH00 25 Nov, 2016 3.60.20.10 Assigned
5l5wI00 25 Nov, 2016 3.60.20.10 Assigned
5l5wJ00 25 Nov, 2016 3.60.20.10 Assigned
5l5wK00 25 Nov, 2016 3.60.20.10 Assigned
5l5wL00 25 Nov, 2016 3.60.20.10 Assigned
5l5wM00 25 Nov, 2016 3.60.20.10 Assigned
5l5wN00 25 Nov, 2016 3.60.20.10 Assigned
5l5wO00 25 Nov, 2016 3.60.20.10 Assigned
5l5wP00 25 Nov, 2016 3.60.20.10 Assigned
5l5wQ00 25 Nov, 2016 3.60.20.10 Assigned
5l5wR00 25 Nov, 2016 3.60.20.10 Assigned
5l5wS00 25 Nov, 2016 3.60.20.10 Assigned
5l5wT00 25 Nov, 2016 3.60.20.10 Assigned
5l5wU00 25 Nov, 2016 3.60.20.10 Assigned
5l5wV00 25 Nov, 2016 3.60.20.10 Assigned
5l5wW00 25 Nov, 2016 3.60.20.10 Assigned
5l5wX00 25 Nov, 2016 3.60.20.10 Assigned
5l5wY00 25 Nov, 2016 3.60.20.10 Assigned
5l5wZ00 25 Nov, 2016 3.60.20.10 Assigned

UniProtKB Entries (32)

Accession Gene ID Taxon Description
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P28074 PSB5_HUMAN Homo sapiens Proteasome subunit beta type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P28074 PSB5_HUMAN Homo sapiens Proteasome subunit beta type-5
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1