PDB Information

PDB5L5O
MethodX-RAY DIFFRACTION
Host OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Gene SourceHomo sapiens
Primary Citation
A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit beta 5i.
Huber, E.M., Heinemeyer, W., de Bruin, G., Overkleeft, H.S., Groll, M.
EMBO J.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-05-28
Resolution2.600
CATH Insert Date20 Nov, 2016

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
a 21 Nov, 2016 Chopped
A 21 Nov, 2016 Chopped
b 21 Nov, 2016 Chopped
B 21 Nov, 2016 Chopped
C 21 Nov, 2016 Chopped
D 21 Nov, 2016 Chopped
E 21 Nov, 2016 Chopped
F 21 Nov, 2016 Chopped
G 21 Nov, 2016 Chopped
H 21 Nov, 2016 Chopped
I 21 Nov, 2016 Chopped
J 21 Nov, 2016 Chopped
K 21 Nov, 2016 Chopped
L 21 Nov, 2016 Chopped
M 21 Nov, 2016 Chopped
N 21 Nov, 2016 Chopped
O 21 Nov, 2016 Chopped
P 21 Nov, 2016 Chopped
Q 21 Nov, 2016 Chopped
R 21 Nov, 2016 Chopped
S 21 Nov, 2016 Chopped
T 21 Nov, 2016 Chopped
U 21 Nov, 2016 Chopped
V 21 Nov, 2016 Chopped
W 21 Nov, 2016 Chopped
X 21 Nov, 2016 Chopped
Y 21 Nov, 2016 Chopped
Z 21 Nov, 2016 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
5l5oa00 25 Nov, 2016 3.60.20.10 Assigned
5l5oA00 25 Nov, 2016 3.60.20.10 Assigned
5l5ob00 25 Nov, 2016 3.60.20.10 Assigned
5l5oB00 25 Nov, 2016 3.60.20.10 Assigned
5l5oC00 25 Nov, 2016 3.60.20.10 Assigned
5l5oD00 25 Nov, 2016 3.60.20.10 Assigned
5l5oE00 25 Nov, 2016 3.60.20.10 Assigned
5l5oF00 25 Nov, 2016 3.60.20.10 Assigned
5l5oG00 25 Nov, 2016 3.60.20.10 Assigned
5l5oH00 25 Nov, 2016 3.60.20.10 Assigned
5l5oI00 25 Nov, 2016 3.60.20.10 Assigned
5l5oJ00 25 Nov, 2016 3.60.20.10 Assigned
5l5oK00 25 Nov, 2016 3.60.20.10 Assigned
5l5oL00 25 Nov, 2016 3.60.20.10 Assigned
5l5oM00 25 Nov, 2016 3.60.20.10 Assigned
5l5oN00 25 Nov, 2016 3.60.20.10 Assigned
5l5oO00 25 Nov, 2016 3.60.20.10 Assigned
5l5oP00 25 Nov, 2016 3.60.20.10 Assigned
5l5oQ00 25 Nov, 2016 3.60.20.10 Assigned
5l5oR00 25 Nov, 2016 3.60.20.10 Assigned
5l5oS00 25 Nov, 2016 3.60.20.10 Assigned
5l5oT00 25 Nov, 2016 3.60.20.10 Assigned
5l5oU00 25 Nov, 2016 3.60.20.10 Assigned
5l5oV00 25 Nov, 2016 3.60.20.10 Assigned
5l5oW00 25 Nov, 2016 3.60.20.10 Assigned
5l5oX00 25 Nov, 2016 3.60.20.10 Assigned
5l5oY00 25 Nov, 2016 3.60.20.10 Assigned
5l5oZ00 25 Nov, 2016 3.60.20.10 Assigned

UniProtKB Entries (32)

Accession Gene ID Taxon Description
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P28062 PSB8_HUMAN Homo sapiens Proteasome subunit beta type-8
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P28062 PSB8_HUMAN Homo sapiens Proteasome subunit beta type-8
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P20618 PSB1_HUMAN Homo sapiens Proteasome subunit beta type-1
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5