Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells.
Jones, S., Ahmet, J., Ayton, K., Ball, M., Cockerill, M., Fairweather, E., Hamilton, N., Harper, P., Hitchin, J., Jordan, A., Levy, C., Lopez, R., McKenzie, E., Packer, M., Plant, D., Simpson, I., Simpson, P., Sinclair, I., Somervaille, T.C., Small, H., Spencer, G.J., Thomson, G., Tonge, M., Waddell, I., Walsh, J., Waszkowycz, B., Wigglesworth, M., Wiseman, D.H., Ogilvie, D.
J.Med.Chem.
