PDB Information

PDB5L2Y
MethodX-RAY DIFFRACTION
Host OrganismCricetinae
Gene SourceHomo sapiens
Primary Citation
Synthesis and P1' SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors.
Ladziata, V.U., Glunz, P.W., Zou, Y., Zhang, X., Jiang, W., Jacutin-Porte, S., Cheney, D.L., Wei, A., Luettgen, J.M., Harper, T.M., Wong, P.C., Seiffert, D., Wexler, R.R., Priestley, E.S.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-08-02
Resolution1.820
CATH Insert Date09 Oct, 2016

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
H 10 Oct, 2016 Chopped
L 10 Oct, 2016 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
5l2yH01 13 Oct, 2016 2.40.10.10 Assigned
5l2yH02 13 Oct, 2016 2.40.10.10 Assigned
5l2yL00 15 Oct, 2016 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII