PDB 5kup

PDB Information

PDB5KUP
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations.
Johnson, A.R., Kohli, P.B., Katewa, A., Gogol, E., Belmont, L.D., Choy, R., Penuel, E., Burton, L., Eigenbrot, C., Yu, C., Ortwine, D.F., Bowman, K., Franke, Y., Tam, C., Estevez, A., Mortara, K., Wu, J., Li, H., Lin, M., Bergeron, P., Crawford, J.J., Young, W.B.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2016-07-13
Resolution1.390
CATH Insert Date02 Oct, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5kupA01 06 Oct, 2016 3.30.200.20 Assigned
5kupA02 06 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK