PDB Information

PDB5KDT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.
Volgraf, M., Sellers, B.D., Jiang, Y., Wu, G., Ly, C.Q., Villemure, E., Pastor, R.M., Yuen, P.W., Lu, A., Luo, X., Liu, M., Zhang, S., Sun, L., Fu, Y., Lupardus, P.J., Wallweber, H.J., Liederer, B.M., Deshmukh, G., Plise, E., Tay, S., Reynen, P., Herrington, J., Gustafson, A., Liu, Y., Dirksen, A., Dietz, M.G., Liu, Y., Wang, T.M., Hanson, J.E., Hackos, D., Scearce-Levie, K., Schwarz, J.B.
J. Med. Chem.
HeaderTransport Protein
Released2016-06-08
Resolution2.440
CATH Insert Date07 Aug, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Aug, 2016 Chopped
B 08 Aug, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5kdtA01 01 Sep, 2016 3.40.190.10 Assigned
5kdtA02 01 Sep, 2016 3.40.190.10 Assigned
5kdtB01 01 Sep, 2016 3.40.190.10 Assigned
5kdtB02 01 Sep, 2016 3.40.190.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q05586 NMDZ1_HUMAN Homo sapiens Glutamate receptor ionotropic, NMDA 1
Q12879 NMDE1_HUMAN Homo sapiens Glutamate receptor ionotropic, NMDA 2A
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