PDB 5k4l

PDB Information

PDB5K4L
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.
Labadie, S.S., Dragovich, P.S., Cummings, R.T., Deshmukh, G., Gustafson, A., Han, N., Harmange, J.C., Kiefer, J.R., Li, Y., Liang, J., Liederer, B.M., Liu, Y., Manieri, W., Mao, W., Murray, L., Ortwine, D.F., Trojer, P., VanderPorten, E., Vinogradova, M., Wen, L.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase/Inhibitor
Released2016-05-20
Resolution3.180
CATH Insert Date04 Sep, 2016

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2016 Chopped
B 05 Sep, 2016 Chopped
F 05 Sep, 2016 Rejected
G 05 Sep, 2016 Rejected

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5k4lA01 16 Feb, 2017 2.60.120.650 Assigned
5k4lA02 16 Feb, 2017 1.10.150.60 Assigned
5k4lA03 16 Feb, 2017 Holding pen
5k4lB01 16 Feb, 2017 2.60.120.650 Assigned
5k4lB02 16 Feb, 2017 1.10.150.60 Assigned
5k4lB03 16 Feb, 2017 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29375 KDM5A_HUMAN Homo sapiens Lysine-specific demethylase 5A
P29375 KDM5A_HUMAN Homo sapiens Lysine-specific demethylase 5A