PDB Information

PDB5K32
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
4-Amino-7,8-dihydro-1,6-naphthyridin-5(6 H)-ones as Inhaled Phosphodiesterase Type 4 (PDE4) Inhibitors: Structural Biology and Structure-Activity Relationships.
Roberts, R.S., Sevilla, S., Ferrer, M., Taltavull, J., Hernandez, B., Segarra, V., Gracia, J., Lehner, M.D., Gavalda, A., Andres, M., Cabedo, J., Vilella, D., Eichhorn, P., Calama, E., Carcasona, C., Miralpeix, M.
J. Med. Chem.
HeaderHydrolase
Released2016-05-19
Resolution1.990
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5k32A00 25 May, 2017 1.10.1300.10 Assigned
5k32B00 25 May, 2017 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
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