PDB Information

PDB5JZ7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Dobson, C.L., Devine, P.W., Phillips, J.J., Higazi, D.R., Lloyd, C., Popovic, B., Arnold, J., Buchanan, A., Lewis, A., Goodman, J., van der Walle, C.F., Thornton, P., Vinall, L., Lowne, D., Aagaard, A., Olsson, L.L., Ridderstad Wollberg, A., Welsh, F., Karamanos, T.K., Pashley, C.L., Iadanza, M.G., Ranson, N.A., Ashcroft, A.E., Kippen, A.D., Vaughan, T.J., Radford, S.E., Lowe, D.C.
Sci Rep
HeaderSignaling Protein
Released2016-05-16
Resolution3.400
CATH Insert Date07 May, 2017

PDB Images (25)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped
E 08 May, 2017 Chopped
F 08 May, 2017 Chopped
G 08 May, 2017 Chopped
H 08 May, 2017 Chopped
I 08 May, 2017 Chopped
J 08 May, 2017 Chopped
K 08 May, 2017 Chopped
L 08 May, 2017 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5jz7A00 13 May, 2017 2.10.90.10 Assigned
5jz7B00 13 May, 2017 2.10.90.10 Assigned
5jz7C00 13 May, 2017 2.60.40.10 Assigned
5jz7D00 13 May, 2017 2.60.40.10 Assigned
5jz7E00 13 May, 2017 2.10.90.10 Assigned
5jz7F00 13 May, 2017 2.10.90.10 Assigned
5jz7G00 13 May, 2017 2.60.40.10 Assigned
5jz7H00 13 May, 2017 2.60.40.10 Assigned
5jz7I00 13 May, 2017 2.60.40.10 Assigned
5jz7J00 13 May, 2017 2.60.40.10 Assigned
5jz7K00 13 May, 2017 2.60.40.10 Assigned
5jz7L00 13 May, 2017 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P01138 NGF_HUMAN Homo sapiens Beta-nerve growth factor
P01138 NGF_HUMAN Homo sapiens Beta-nerve growth factor
P01138 NGF_HUMAN Homo sapiens Beta-nerve growth factor
P01138 NGF_HUMAN Homo sapiens Beta-nerve growth factor
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