Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177).
De Lucca, G.V., Shi, Q., Liu, Q., Batt, D.G., Beaudoin Bertrand, M., Rampulla, R., Mathur, A., Discenza, L., D'Arienzo, C., Dai, J., Obermeier, M., Vickery, R., Zhang, Y., Yang, Z., Marathe, P., Tebben, A.J., Muckelbauer, J.K., Chang, C.J., Zhang, H., Gillooly, K., Taylor, T., Pattoli, M.A., Skala, S., Kukral, D.W., McIntyre, K.W., Salter-Cid, L., Fura, A., Burke, J.R., Barrish, J.C., Carter, P.H., Tino, J.A.
J.Med.Chem.