PDB Information

PDB5JRQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAF(V600E) Conformation.
Grasso, M., Estrada, M.A., Ventocilla, C., Samanta, M., Maksimoska, J., Villanueva, J., Winkler, J.D., Marmorstein, R.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2016-05-06
Resolution2.290
CATH Insert Date02 Oct, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped
B 03 Oct, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5jrqA01 06 Oct, 2016 3.30.200.20 Assigned
5jrqA02 06 Oct, 2016 1.10.510.10 Assigned
5jrqB01 07 Oct, 2016 3.30.200.20 Assigned
5jrqB02 07 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
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