PDB 5jhs

PDB Links
Overview

PDB Information

PDB	5JHS
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Structure-Based Design of beta 5c Selective Inhibitors of Human Constitutive Proteasomes. Xin, B.T., de Bruin, G., Huber, E.M., Besse, A., Florea, B.I., Filippov, D.V., van der Marel, G.A., Kisselev, A.F., van der Stelt, M., Driessen, C., Groll, M., Overkleeft, H.S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-04-21
Resolution	3.000
CATH Insert Date	14 Aug, 2016

PDB Images (57)

5jhs

PDB 5jhs

5jhsa

PDB Chain 5jhsa

5jhsA

PDB Chain 5jhsA

5jhsb

PDB Chain 5jhsb

5jhsB

PDB Chain 5jhsB

5jhsC

PDB Chain 5jhsC

5jhsD

PDB Chain 5jhsD

5jhsE

PDB Chain 5jhsE

5jhsF

PDB Chain 5jhsF

5jhsG

PDB Chain 5jhsG

5jhsH

PDB Chain 5jhsH

5jhsI

PDB Chain 5jhsI

5jhsJ

PDB Chain 5jhsJ

5jhsK

PDB Chain 5jhsK

5jhsL

PDB Chain 5jhsL

5jhsM

PDB Chain 5jhsM

5jhsN

PDB Chain 5jhsN

5jhsO

PDB Chain 5jhsO

5jhsP

PDB Chain 5jhsP

5jhsQ

PDB Chain 5jhsQ

5jhsR

PDB Chain 5jhsR

5jhsS

PDB Chain 5jhsS

5jhsT

PDB Chain 5jhsT

5jhsU

PDB Chain 5jhsU

5jhsV

PDB Chain 5jhsV

5jhsW

PDB Chain 5jhsW

5jhsX

PDB Chain 5jhsX

5jhsY

PDB Chain 5jhsY

5jhsZ

PDB Chain 5jhsZ

5jhsa00

CATH Domain 5jhsa00

5jhsA00

CATH Domain 5jhsA00

5jhsb00

CATH Domain 5jhsb00

5jhsB00

CATH Domain 5jhsB00

5jhsC00

CATH Domain 5jhsC00

5jhsD00

CATH Domain 5jhsD00

5jhsE00

CATH Domain 5jhsE00

5jhsF00

CATH Domain 5jhsF00

5jhsG00

CATH Domain 5jhsG00

5jhsH00

CATH Domain 5jhsH00

5jhsI00

CATH Domain 5jhsI00

5jhsJ00

CATH Domain 5jhsJ00

5jhsK00

CATH Domain 5jhsK00

5jhsL00

CATH Domain 5jhsL00

5jhsM00

CATH Domain 5jhsM00

5jhsN00

CATH Domain 5jhsN00

5jhsO00

CATH Domain 5jhsO00

5jhsP00

CATH Domain 5jhsP00

5jhsQ00

CATH Domain 5jhsQ00

5jhsR00

CATH Domain 5jhsR00

5jhsS00

CATH Domain 5jhsS00

5jhsT00

CATH Domain 5jhsT00

5jhsU00

CATH Domain 5jhsU00

5jhsV00

CATH Domain 5jhsV00

5jhsW00

CATH Domain 5jhsW00

5jhsX00

CATH Domain 5jhsX00

5jhsY00

CATH Domain 5jhsY00

5jhsZ00

CATH Domain 5jhsZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	15 Aug, 2016	Chopped
A	15 Aug, 2016	Chopped
b	15 Aug, 2016	Chopped
B	15 Aug, 2016	Chopped
C	15 Aug, 2016	Chopped
D	15 Aug, 2016	Chopped
E	15 Aug, 2016	Chopped
F	15 Aug, 2016	Chopped
G	15 Aug, 2016	Chopped
H	15 Aug, 2016	Chopped
I	15 Aug, 2016	Chopped
J	15 Aug, 2016	Chopped
K	15 Aug, 2016	Chopped
L	15 Aug, 2016	Chopped
M	15 Aug, 2016	Chopped
N	15 Aug, 2016	Chopped
O	15 Aug, 2016	Chopped
P	15 Aug, 2016	Chopped
Q	15 Aug, 2016	Chopped
R	15 Aug, 2016	Chopped
S	15 Aug, 2016	Chopped
T	15 Aug, 2016	Chopped
U	15 Aug, 2016	Chopped
V	15 Aug, 2016	Chopped
W	15 Aug, 2016	Chopped
X	15 Aug, 2016	Chopped
Y	15 Aug, 2016	Chopped
Z	15 Aug, 2016	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5jhsa00	01 Sep, 2016	3.60.20.10	Assigned
5jhsA00	01 Sep, 2016	3.60.20.10	Assigned
5jhsb00	20 Oct, 2016	3.60.20.10	Assigned
5jhsB00	01 Sep, 2016	3.60.20.10	Assigned
5jhsC00	01 Sep, 2016	3.60.20.10	Assigned
5jhsD00	01 Sep, 2016	3.60.20.10	Assigned
5jhsE00	01 Sep, 2016	3.60.20.10	Assigned
5jhsF00	01 Sep, 2016	3.60.20.10	Assigned
5jhsG00	01 Sep, 2016	3.60.20.10	Assigned
5jhsH00	01 Sep, 2016	3.60.20.10	Assigned
5jhsI00	01 Sep, 2016	3.60.20.10	Assigned
5jhsJ00	01 Sep, 2016	3.60.20.10	Assigned
5jhsK00	01 Sep, 2016	3.60.20.10	Assigned
5jhsL00	01 Sep, 2016	3.60.20.10	Assigned
5jhsM00	01 Sep, 2016	3.60.20.10	Assigned
5jhsN00	20 Oct, 2016	3.60.20.10	Assigned
5jhsO00	01 Sep, 2016	3.60.20.10	Assigned
5jhsP00	01 Sep, 2016	3.60.20.10	Assigned
5jhsQ00	01 Sep, 2016	3.60.20.10	Assigned
5jhsR00	01 Sep, 2016	3.60.20.10	Assigned
5jhsS00	01 Sep, 2016	3.60.20.10	Assigned
5jhsT00	01 Sep, 2016	3.60.20.10	Assigned
5jhsU00	01 Sep, 2016	3.60.20.10	Assigned
5jhsV00	01 Sep, 2016	3.60.20.10	Assigned
5jhsW00	01 Sep, 2016	3.60.20.10	Assigned
5jhsX00	01 Sep, 2016	3.60.20.10	Assigned
5jhsY00	01 Sep, 2016	3.60.20.10	Assigned
5jhsZ00	01 Sep, 2016	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5