PDB Information

PDB5JGB
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)
Muraoka, T., Ide, M., Morikami, K., Irie, M., Nakamura, M., Miura, T., Kamikawa, T., Nishihara, M., Kashiwagi, H.
Bioorg.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-04-20
Resolution2.800
CATH Insert Date14 Aug, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Aug, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5jgbA01 01 Sep, 2016 3.30.200.20 Assigned
5jgbA02 01 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q15750 TAB1_HUMAN Homo sapiens TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
O43318 M3K7_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 7
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