PDB 5jfs

PDB Information

PDB5JFS
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain.
Skerratt, S.E., Andrews, M., Bagal, S.K., Bilsland, J., Brown, D., Bungay, P.J., Cole, S., Gibson, K.R., Jones, R., Morao, I., Nedderman, A., Omoto, K., Robinson, C., Ryckmans, T., Skinner, K., Stupple, P., Waldron, G.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-04-19
Resolution2.070
CATH Insert Date07 May, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5jfsA01 12 May, 2017 3.30.200.20 Assigned
5jfsA02 12 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P04629 NTRK1_HUMAN Homo sapiens High affinity nerve growth factor receptor