PDB Information

PDB5J8I
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-guided development of covalent TAK1 inhibitors.
Tan, L., Gurbani, D., Weisberg, E.L., Hunter, J.C., Li, L., Jones, D.S., Ficarro, S.B., Mowafy, S., Tam, C.P., Rao, S., Du, G., Griffin, J.D., Sorger, P.K., Marto, J.A., Westover, K.D., Gray, N.S.
Bioorg. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-04-07
Resolution2.400
CATH Insert Date07 May, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5j8iA01 12 May, 2017 3.30.200.20 Assigned
5j8iA02 12 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q15750 TAB1_HUMAN Homo sapiens TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
O43318 M3K7_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 7
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