PDB 5j7b

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Overview

PDB Information

PDB	5J7B
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase. Haile, P.A., Votta, B.J., Marquis, R.W., Bury, M.J., Mehlmann, J.F., Singhaus, R., Charnley, A.K., Lakdawala, A.S., Convery, M.A., Lipshutz, D.B., Desai, B.M., Swift, B., Capriotti, C.A., Berger, S.B., Mahajan, M.K., Reilly, M.A., Rivera, E.J., Sun, H.H., Nagilla, R., Beal, A.M., Finger, J.N., Cook, M.N., King, B.W., Ouellette, M.T., Totoritis, R.D., Pierdomenico, M., Negroni, A., Stronati, L., Cucchiara, S., Ziokowski, B., Vossenkamper, A., MacDonald, T.T., Gough, P.J., Bertin, J., Casillas, L.N. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-04-06
Resolution	2.530
CATH Insert Date	29 May, 2016

PDB Images (5)

Image of CATH 5j7b

5j7b

PDB 5j7b

Image of CATH 5j7bA

5j7bA

PDB Chain 5j7bA

Image of CATH 5j7bB

5j7bB

PDB Chain 5j7bB

Image of CATH 5j7bA00

5j7bA00

CATH Domain 5j7bA00

Image of CATH 5j7bB00

5j7bB00

CATH Domain 5j7bB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	30 May, 2016	Chopped
B	30 May, 2016	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5j7bA00	19 Jul, 2016	1.10.510.10	Assigned
5j7bB00	19 Jul, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O43353	RIPK2_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 2
O43353	RIPK2_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 2