PDB 5j79

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Overview

PDB Information

PDB	5J79
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase. Haile, P.A., Votta, B.J., Marquis, R.W., Bury, M.J., Mehlmann, J.F., Singhaus, R., Charnley, A.K., Lakdawala, A.S., Convery, M.A., Lipshutz, D.B., Desai, B.M., Swift, B., Capriotti, C.A., Berger, S.B., Mahajan, M.K., Reilly, M.A., Rivera, E.J., Sun, H.H., Nagilla, R., Beal, A.M., Finger, J.N., Cook, M.N., King, B.W., Ouellette, M.T., Totoritis, R.D., Pierdomenico, M., Negroni, A., Stronati, L., Cucchiara, S., Ziokowski, B., Vossenkamper, A., MacDonald, T.T., Gough, P.J., Bertin, J., Casillas, L.N. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-04-06
Resolution	2.690
CATH Insert Date	29 May, 2016

PDB Images (5)

Image of CATH 5j79

5j79

PDB 5j79

Image of CATH 5j79A

5j79A

PDB Chain 5j79A

Image of CATH 5j79B

5j79B

PDB Chain 5j79B

Image of CATH 5j79A00

5j79A00

CATH Domain 5j79A00

Image of CATH 5j79B00

5j79B00

CATH Domain 5j79B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	30 May, 2016	Chopped
B	30 May, 2016	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5j79A00	19 Jul, 2016	1.10.510.10	Assigned
5j79B00	19 Jul, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O43353	RIPK2_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 2
O43353	RIPK2_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 2