PDB Information

PDB5J3P
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Hornyak, P., Askwith, T., Walker, S., Komulainen, E., Paradowski, M., Pennicott, L.E., Bartlett, E.J., Brissett, N.C., Raoof, A., Watson, M., Jordan, A.M., Ogilvie, D.J., Ward, S.E., Atack, J.R., Pearl, L.H., Caldecott, K.W., Oliver, A.W.
Biochem.J.
HeaderHydrolase
Released2016-03-31
Resolution3.100
CATH Insert Date15 May, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5j3pA00 19 Jul, 2016 3.60.10.10 Assigned
5j3pB00 19 Jul, 2016 3.60.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O95551 TYDP2_HUMAN Homo sapiens Tyrosyl-DNA phosphodiesterase 2
O95551 TYDP2_HUMAN Homo sapiens Tyrosyl-DNA phosphodiesterase 2