PDB 5izq

PDB Information

PDB5IZQ
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
Golani, L.K., Wallace-Povirk, A., Deis, S.M., Wong, J., Ke, J., Gu, X., Raghavan, S., Wilson, M.R., Li, X., Polin, L., de Waal, P.W., White, K., Kushner, J., O'Connor, C., Hou, Z., Xu, H.E., Melcher, K., Dann, C.E., Matherly, L.H., Gangjee, A.
J.Med.Chem.
HeaderSignaling Protein
Released2016-03-25
Resolution3.600
CATH Insert Date14 Aug, 2016

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 15 Aug, 2016 Chopped
B 15 Aug, 2016 Chopped
C 15 Aug, 2016 Chopped
D 15 Aug, 2016 Chopped
E 15 Aug, 2016 Chopped
F 15 Aug, 2016 Chopped
G 15 Aug, 2016 Chopped
H 15 Aug, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5izqA00 01 Sep, 2016 Holding pen
5izqB00 01 Sep, 2016 Holding pen
5izqC00 01 Sep, 2016 Holding pen
5izqD00 01 Sep, 2016 Holding pen
5izqE00 01 Sep, 2016 Holding pen
5izqF00 01 Sep, 2016 Holding pen
5izqG00 01 Sep, 2016 Holding pen
5izqH00 01 Sep, 2016 Holding pen

UniProtKB Entries (0)

Accession Gene ID Taxon Description