PDB 5ixy

PDB Information

PDB5IXY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Purkey, H.E., Robarge, K., Chen, J., Chen, Z., Corson, L.B., Ding, C.Z., DiPasquale, A.G., Dragovich, P.S., Eigenbrot, C., Evangelista, M., Fauber, B.P., Gao, Z., Ge, H., Hitz, A., Ho, Q., Labadie, S.S., Lai, K.W., Liu, W., Liu, Y., Li, C., Ma, S., Malek, S., O'Brien, T., Pang, J., Peterson, D., Salphati, L., Sideris, S., Ultsch, M., Wei, B., Yen, I., Yue, Q., Zhang, H., Zhou, A.
Acs Med.Chem.Lett.
HeaderOxireductase/Oxireductase Inhibitor
Released2016-03-23
Resolution3.000
CATH Insert Date09 Oct, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 10 Oct, 2016 Chopped
B 10 Oct, 2016 Chopped
C 10 Oct, 2016 Chopped
D 10 Oct, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5ixyA01 15 Oct, 2016 3.40.50.720 Assigned
5ixyA02 15 Oct, 2016 3.90.110.10 Assigned
5ixyB01 15 Oct, 2016 3.40.50.720 Assigned
5ixyB02 15 Oct, 2016 3.90.110.10 Assigned
5ixyC01 13 Oct, 2016 3.40.50.720 Assigned
5ixyC02 13 Oct, 2016 3.90.110.10 Assigned
5ixyD01 14 Oct, 2016 3.40.50.720 Assigned
5ixyD02 14 Oct, 2016 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
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