PDB 5icp

PDB Links
Overview

PDB Information

PDB	5ICP
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening. Czodrowski, P., Mallinger, A., Wienke, D., Esdar, C., Poschke, O., Busch, M., Rohdich, F., Eccles, S.A., Ortiz-Ruiz, M.J., Schneider, R., Raynaud, F.I., Clarke, P.A., Musil, D., Schwarz, D., Dale, T., Urbahns, K., Blagg, J., Schiemann, K. J. Med. Chem.
Header	Transferase
Released	2016-02-23
Resolution	2.180
CATH Insert Date	25 Dec, 2016

PDB Images (7)

Image of CATH 5icp

5icp

PDB 5icp

Image of CATH 5icpA

5icpA

PDB Chain 5icpA

Image of CATH 5icpB

5icpB

PDB Chain 5icpB

Image of CATH 5icpA01

5icpA01

CATH Domain 5icpA01

Image of CATH 5icpA02

5icpA02

CATH Domain 5icpA02

Image of CATH 5icpB01

5icpB01

CATH Domain 5icpB01

Image of CATH 5icpB02

5icpB02

CATH Domain 5icpB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	26 Dec, 2016	Chopped
B	26 Dec, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5icpA01	29 Dec, 2016	3.30.200.20	Assigned
5icpA02	29 Dec, 2016	1.10.510.10	Assigned
5icpB01	29 Dec, 2016	1.10.472.10	Assigned
5icpB02	29 Dec, 2016	1.10.472.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P49336	CDK8_HUMAN	Homo sapiens	Cyclin-dependent kinase 8
P24863	CCNC_HUMAN	Homo sapiens	Cyclin-C