PDB 5hne

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Overview

PDB Information

PDB	5HNE
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors. Deng, H., Zhou, J., Sundersingh, F., Messer, J.A., Somers, D.O., Ajakane, M., Arico-Muendel, C.C., Beljean, A., Belyanskaya, S.L., Bingham, R., Blazensky, E., Boullay, A.B., Boursier, E., Chai, J., Carter, P., Chung, C.W., Daugan, A., Ding, Y., Herry, K., Hobbs, C., Humphries, E., Kollmann, C., Nguyen, V.L., Nicodeme, E., Smith, S.E., Dodic, N., Ancellin, N. Acs Med.Chem.Lett.
Header	Transferase
Released	2016-01-18
Resolution	2.040
CATH Insert Date	15 May, 2016

PDB Images (7)

Image of CATH 5hne

5hne

PDB 5hne

Image of CATH 5hneA

5hneA

PDB Chain 5hneA

Image of CATH 5hneB

5hneB

PDB Chain 5hneB

Image of CATH 5hneA01

5hneA01

CATH Domain 5hneA01

Image of CATH 5hneA02

5hneA02

CATH Domain 5hneA02

Image of CATH 5hneB01

5hneB01

CATH Domain 5hneB01

Image of CATH 5hneB02

5hneB02

CATH Domain 5hneB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 May, 2016	Chopped
B	16 May, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hneA01	16 Jul, 2016	3.30.470.10	Assigned
5hneA02	16 Jul, 2016	3.20.10.10	Assigned
5hneB01	17 Jul, 2016	3.30.470.10	Assigned
5hneB02	17 Jul, 2016	3.20.10.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O15382	BCAT2_HUMAN	Homo sapiens	Branched-chain-amino-acid aminotransferase, mitochondrial
O15382	BCAT2_HUMAN	Homo sapiens	Branched-chain-amino-acid aminotransferase, mitochondrial