PDB Information

PDB5HLW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).
Ugolini, A., Kenigsberg, M., Rak, A., Vallee, F., Houtmann, J., Lowinski, M., Capdevila, C., Khider, J., Albert, E., Martinet, N., Nemecek, C., Grapinet, S., Bacque, E., Roesner, M., Delaisi, C., Calvet, L., Bonche, F., Semiond, D., Egile, C., Goulaouic, H., Schio, L.
J.Med.Chem.
HeaderTransferase
Released2016-01-15
Resolution1.970
CATH Insert Date04 Dec, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Dec, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5hlwA01 08 Dec, 2016 3.30.200.20 Assigned
5hlwA02 08 Dec, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
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