PDB Information

PDB5HCZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor.
Chan, B.K., Hanan, E.J., Bowman, K.K., Bryan, M.C., Burdick, D., Chan, E., Chen, Y., Clausen, S., Dela Vega, T., Dotson, J., Eigenbrot, C., Elliott, R.L., Heald, R.A., Jackson, P.S., Knight, J.D., La, H., Lainchbury, M.D., Malek, S., Purkey, H.E., Schaefer, G., Schmidt, S., Seward, E.M., Sideris, S., Shao, L., Wang, S., Yeap, S.K., Yen, I., Yu, C., Heffron, T.P.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-01-04
Resolution2.620
CATH Insert Date06 Nov, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5hczA01 10 Nov, 2016 3.30.200.20 Assigned
5hczA02 10 Nov, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor