PDB Information

PDB5HCV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists.
Lotesta, S.D., Marcus, A.P., Zheng, Y., Leftheris, K., Noto, P.B., Meng, S., Kandpal, G., Chen, G., Zhou, J., McKeever, B., Bukhtiyarov, Y., Zhao, Y., Lala, D.S., Singh, S.B., McGeehan, G.M.
Bioorg.Med.Chem.
HeaderSignaling Protein
Released2016-01-04
Resolution2.500
CATH Insert Date10 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
5hcvA00 13 May, 2016 1.10.565.10 Assigned
5hcvB00 13 May, 2016 1.10.565.10 Assigned
5hcvC00 13 May, 2016 1.10.565.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P08235 MCR_HUMAN Homo sapiens Mineralocorticoid receptor
P08235 MCR_HUMAN Homo sapiens Mineralocorticoid receptor
P08235 MCR_HUMAN Homo sapiens Mineralocorticoid receptor