PDB 5hbj

PDB Links
Overview

PDB Information

PDB	5HBJ
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. Mallinger, A., Schiemann, K., Rink, C., Stieber, F., Calderini, M., Crumpler, S., Stubbs, M., Adeniji-Popoola, O., Poeschke, O., Busch, M., Czodrowski, P., Musil, D., Schwarz, D., Ortiz-Ruiz, M.J., Schneider, R., Thai, C., Valenti, M., de Haven Brandon, A., Burke, R., Workman, P., Dale, T., Wienke, D., Clarke, P.A., Esdar, C., Raynaud, F.I., Eccles, S.A., Rohdich, F., Blagg, J. J.Med.Chem.
Header	Transferase
Released	2015-12-31
Resolution	3.000
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 5hbj

5hbj

PDB 5hbj

Image of CATH 5hbjA

5hbjA

PDB Chain 5hbjA

Image of CATH 5hbjB

5hbjB

PDB Chain 5hbjB

Image of CATH 5hbjA01

5hbjA01

CATH Domain 5hbjA01

Image of CATH 5hbjA02

5hbjA02

CATH Domain 5hbjA02

Image of CATH 5hbjB01

5hbjB01

CATH Domain 5hbjB01

Image of CATH 5hbjB02

5hbjB02

CATH Domain 5hbjB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hbjA01	13 May, 2016	3.30.200.20	Assigned
5hbjA02	13 May, 2016	1.10.510.10	Assigned
5hbjB01	13 May, 2016	1.10.472.10	Assigned
5hbjB02	13 May, 2016	1.10.472.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P24863	CCNC_HUMAN	Homo sapiens	Cyclin-C
P49336	CDK8_HUMAN	Homo sapiens	Cyclin-dependent kinase 8