PDB 5hbe

PDB Links
Overview

PDB Information

PDB	5HBE
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. Mallinger, A., Schiemann, K., Rink, C., Stieber, F., Calderini, M., Crumpler, S., Stubbs, M., Adeniji-Popoola, O., Poeschke, O., Busch, M., Czodrowski, P., Musil, D., Schwarz, D., Ortiz-Ruiz, M.J., Schneider, R., Thai, C., Valenti, M., de Haven Brandon, A., Burke, R., Workman, P., Dale, T., Wienke, D., Clarke, P.A., Esdar, C., Raynaud, F.I., Eccles, S.A., Rohdich, F., Blagg, J. J.Med.Chem.
Header	Transferase
Released	2015-12-31
Resolution	2.380
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 5hbe

5hbe

PDB 5hbe

Image of CATH 5hbeA

5hbeA

PDB Chain 5hbeA

Image of CATH 5hbeB

5hbeB

PDB Chain 5hbeB

Image of CATH 5hbeA01

5hbeA01

CATH Domain 5hbeA01

Image of CATH 5hbeA02

5hbeA02

CATH Domain 5hbeA02

Image of CATH 5hbeB01

5hbeB01

CATH Domain 5hbeB01

Image of CATH 5hbeB02

5hbeB02

CATH Domain 5hbeB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hbeA01	13 May, 2016	3.30.200.20	Assigned
5hbeA02	13 May, 2016	1.10.510.10	Assigned
5hbeB01	13 May, 2016	1.10.472.10	Assigned
5hbeB02	13 May, 2016	1.10.472.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P24863	CCNC_HUMAN	Homo sapiens	Cyclin-C
P49336	CDK8_HUMAN	Homo sapiens	Cyclin-dependent kinase 8