PDB Information

PDB5H1T
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli 'BL21-Gold(DE3)pLysS AG'
Gene SourceHomo sapiens
Primary Citation
The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network
Liu, J., Li, F., Bao, H., Jiang, Y., Zhang, S., Ma, R., Gao, J., Wu, J., Ruan, K.
FEBS J.
HeaderTranscription/Transcription Inhibitor
Released2016-10-11
Resolution1.950
CATH Insert Date07 May, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5h1tA01 12 May, 2017 3.30.40.10 Assigned
5h1tA02 12 May, 2017 1.20.920.10 Assigned
5h1tB01 12 May, 2017 3.30.40.10 Assigned
5h1tB02 12 May, 2017 1.20.920.10 Assigned
5h1tC01 12 May, 2017 3.30.40.10 Assigned
5h1tC02 12 May, 2017 1.20.920.10 Assigned
5h1tD01 12 May, 2017 3.30.40.10 Assigned
5h1tD02 12 May, 2017 1.20.920.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O15164 TIF1A_HUMAN Homo sapiens Transcription intermediary factor 1-alpha
O15164 TIF1A_HUMAN Homo sapiens Transcription intermediary factor 1-alpha
O15164 TIF1A_HUMAN Homo sapiens Transcription intermediary factor 1-alpha
O15164 TIF1A_HUMAN Homo sapiens Transcription intermediary factor 1-alpha