PDB Information

PDB5GWI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Wang, Y.R., Chen, S.F., Wu, C.C., Liao, Y.W., Lin, T.S., Liu, K.T., Chen, Y.S., Li, T.K., Chien, T.C., Chan, N.L.
Nucleic Acids Res.
HeaderIsomerase/Dna/Isomerase Inhibitor
Released2016-09-12
Resolution2.740
CATH Insert Date14 Nov, 2017

PDB Images (15)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Rejected
D 14 Nov, 2017 Rejected
E 14 Nov, 2017 Rejected
F 14 Nov, 2017 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5gwiA01 10 Dec, 2017 3.40.50.670 Assigned
5gwiA02 10 Dec, 2017 3.90.199.10 Assigned
5gwiA03 10 Dec, 2017 3.30.1360.40 Assigned
5gwiA04 10 Dec, 2017 1.10.268.10 Assigned
5gwiB01 10 Dec, 2017 3.40.50.670 Assigned
5gwiB02 10 Dec, 2017 3.90.199.10 Assigned
5gwiB03 10 Dec, 2017 3.30.1360.40 Assigned
5gwiB04 10 Dec, 2017 1.10.268.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q02880 TOP2B_HUMAN Homo sapiens DNA topoisomerase 2-beta
Q02880 TOP2B_HUMAN Homo sapiens DNA topoisomerase 2-beta
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