PDB 5fxs

PDB Information

PDB5FXS
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R).
Degorce, S.L., Boyd, S., Curwen, J.O., Ducray, R., Halsall, C.T., Jones, C.D., Lach, F., Lenz, E.M., Pass, M., Pass, S., Trigwell, C.
J. Med. Chem.
HeaderTransferase
Released2016-03-02
Resolution1.900
CATH Insert Date06 Nov, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5fxsA01 09 Nov, 2016 3.30.200.20 Assigned
5fxsA02 09 Nov, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
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