PDB 5fxq

PDB Information

PDB5FXQ
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R).
Degorce, S.L., Boyd, S., Curwen, J.O., Ducray, R., Halsall, C.T., Jones, C.D., Lach, F., Lenz, E.M., Pass, M., Pass, S., Trigwell, C.
J. Med. Chem.
HeaderTransferase
Released2016-03-02
Resolution2.300
CATH Insert Date20 Nov, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5fxqA01 25 Nov, 2016 3.30.200.20 Assigned
5fxqA02 25 Nov, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
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