PDB 5fv2

PDB Information

PDB5FV2
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept.
Walker, A., Chung, C., Neu, M., Burman, M., Batuwangala, T., Jones, G., Tang, C., Steward, M., Mullin, M., Tournier, N., Lewis, A., Korczynska, J., Chung, V., Catchpole, I.
J.Biol.Chem.
HeaderHormone
Released2016-02-02
Resolution3.450
CATH Insert Date10 Apr, 2016

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
V 11 Apr, 2016 Chopped
W 11 Apr, 2016 Chopped
X 11 Apr, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5fv2A00 12 May, 2016 2.60.40.10 Assigned
5fv2B00 12 May, 2016 2.60.40.10 Assigned
5fv2C00 12 May, 2016 2.60.40.10 Assigned
5fv2V00 12 May, 2016 2.10.90.10 Assigned
5fv2W00 12 May, 2016 2.10.90.10 Assigned
5fv2X00 12 May, 2016 2.10.90.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P15692 VEGFA_HUMAN Homo sapiens Vascular endothelial growth factor A
P15692 VEGFA_HUMAN Homo sapiens Vascular endothelial growth factor A
P15692 VEGFA_HUMAN Homo sapiens Vascular endothelial growth factor A