PDB Information

PDB5FV1
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept.
Walker, A., Chung, C., Neu, M., Burman, M., Batuwangala, T., Jones, G., Tang, C., Steward, M., Mullin, M., Tournier, N., Lewis, A., Korczynska, J., Chung, V., Catchpole, I.
J.Biol.Chem.
HeaderImmune System
Released2016-02-02
Resolution2.700
CATH Insert Date10 Apr, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
L 11 Apr, 2016 Chopped
M 11 Apr, 2016 Chopped
V 11 Apr, 2016 Chopped
W 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5fv1L00 12 May, 2016 2.60.40.10 Assigned
5fv1M00 12 May, 2016 2.60.40.10 Assigned
5fv1V00 12 May, 2016 2.10.90.10 Assigned
5fv1W00 12 May, 2016 2.10.90.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15692 VEGFA_HUMAN Homo sapiens Vascular endothelial growth factor A
P15692 VEGFA_HUMAN Homo sapiens Vascular endothelial growth factor A
CATH-Gene3D is a Global Biodata Core Resource Learn more...