PDB Information

PDB5FH6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex.
Sutherell, C.L., Tallant, C., Monteiro, O.P., Yapp, C., Fuchs, J.E., Fedorov, O., Siejka, P., Muller, S., Knapp, S., Brenton, J.D., Brennan, P.E., Ley, S.V.
J.Med.Chem.
HeaderTranscription
Released2015-12-21
Resolution2.300
CATH Insert Date19 Jun, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2016 Chopped
B 20 Jun, 2016 Chopped
C 20 Jun, 2016 Chopped
D 20 Jun, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5fh6A00 16 Jul, 2016 1.20.920.10 Assigned
5fh6B00 16 Jul, 2016 1.20.920.10 Assigned
5fh6C00 16 Jul, 2016 1.20.920.10 Assigned
5fh6D00 16 Jul, 2016 1.20.920.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q86U86 PB1_HUMAN Homo sapiens Protein polybromo-1
Q86U86 PB1_HUMAN Homo sapiens Protein polybromo-1
Q86U86 PB1_HUMAN Homo sapiens Protein polybromo-1
Q86U86 PB1_HUMAN Homo sapiens Protein polybromo-1
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