PDB Information

PDB5FD2
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Purinylpyridinylamino-based DFG-in/ alpha C-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling.
Liu, L., Lee, M.R., Kim, J.L., Whittington, D.A., Bregman, H., Hua, Z., Lewis, R.T., Martin, M.W., Nishimura, N., Potashman, M., Yang, K., Yi, S., Vaida, K.R., Epstein, L.F., Babij, C., Fernando, M., Carnahan, J., Norman, M.H.
Bioorg.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-12-15
Resolution2.890
CATH Insert Date15 May, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5fd2A01 16 Jul, 2016 3.30.200.20 Assigned
5fd2A02 16 Jul, 2016 1.10.510.10 Assigned
5fd2B01 15 Jul, 2016 3.30.200.20 Assigned
5fd2B02 15 Jul, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
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