PDB Information

PDB5FCK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small-molecule factor D inhibitors targeting the alternative complement pathway.
Maibaum, J., Liao, S.M., Vulpetti, A., Ostermann, N., Randl, S., Rudisser, S., Lorthiois, E., Erbel, P., Kinzel, B., Kolb, F.A., Barbieri, S., Wagner, J., Durand, C., Fettis, K., Dussauge, S., Hughes, N., Delgado, O., Hommel, U., Gould, T., Mac Sweeney, A., Gerhartz, B., Cumin, F., Flohr, S., Schubart, A., Jaffee, B., Harrison, R., Risitano, A.M., Eder, J., Anderson, K.
Nat.Chem.Biol.
HeaderHydrolase
Released2015-12-15
Resolution1.860
CATH Insert Date06 Nov, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5fckA01 10 Nov, 2016 2.40.10.10 Assigned
5fckA02 10 Nov, 2016 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00746 CFAD_HUMAN Homo sapiens Complement factor D