PDB Information

PDB5F9E
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKC theta inhibitors.
Katoh, T., Takai, T., Yukawa, T., Tsukamoto, T., Watanabe, E., Mototani, H., Arita, T., Hayashi, H., Nakagawa, H., Klein, M.G., Zou, H., Sang, B.C., Snell, G., Nakada, Y.
Bioorg.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-12-09
Resolution2.000
CATH Insert Date29 May, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5f9eA01 15 Jul, 2016 3.30.200.20 Assigned
5f9eA02 15 Jul, 2016 1.10.510.10 Assigned
5f9eB01 15 Jul, 2016 3.30.200.20 Assigned
5f9eB02 15 Jul, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q04759 KPCT_HUMAN Homo sapiens Protein kinase C theta type
Q04759 KPCT_HUMAN Homo sapiens Protein kinase C theta type