PDB Information

PDB5F1Z
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors.
Yogo, T., Nagamiya, H., Seto, M., Sasaki, S., Shih-Chung, H., Ohba, Y., Tokunaga, N., Lee, G.N., Rhim, C.Y., Yoon, C.H., Cho, S.Y., Skene, R., Yamamoto, S., Satou, Y., Kuno, M., Miyazaki, T., Nakagawa, H., Okabe, A., Marui, S., Aso, K., Yoshida, M.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-12-01
Resolution2.650
CATH Insert Date10 Apr, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5f1zA01 09 May, 2016 3.30.200.20 Assigned
5f1zA02 09 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P29597 TYK2_HUMAN Homo sapiens Non-receptor tyrosine-protein kinase TYK2
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