PDB Information

PDB5ENS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli K-12
Primary Citation
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Sjuts, H., Vargiu, A.V., Kwasny, S.M., Nguyen, S.T., Kim, H.S., Ding, X., Ornik, A.R., Ruggerone, P., Bowlin, T.L., Nikaido, H., Pos, K.M., Opperman, T.J.
Proc.Natl.Acad.Sci.USA
HeaderTransport Protein
Released2015-11-09
Resolution2.800
CATH Insert Date17 Apr, 2016

PDB Images (25)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped
B 18 Apr, 2016 Chopped
C 18 Apr, 2016 Chopped
D 18 Apr, 2016 Chopped
E 18 Apr, 2016 Chopped
F 18 Apr, 2016 Chopped

CATH Domains (18)

Domain ID Date inserted into CATH Superfamily CATH Status
5ensA01 09 Jan, 2018 3.30.70.1430 Assigned
5ensA02 09 Jan, 2018 3.30.70.1320 Assigned
5ensA03 09 Jan, 2018 Holding pen
5ensA04 09 Jan, 2018 3.30.70.1430 Assigned
5ensA05 09 Jan, 2018 3.30.70.1440 Assigned
5ensB01 09 Jan, 2018 3.30.70.1430 Assigned
5ensB02 09 Jan, 2018 3.30.70.1320 Assigned
5ensB03 09 Jan, 2018 Holding pen
5ensB04 09 Jan, 2018 3.30.70.1430 Assigned
5ensB05 09 Jan, 2018 3.30.70.1440 Assigned
5ensC01 09 Jan, 2018 3.30.70.1430 Assigned
5ensC02 09 Jan, 2018 3.30.70.1320 Assigned
5ensC03 09 Jan, 2018 Holding pen
5ensC04 09 Jan, 2018 3.30.70.1430 Assigned
5ensC05 09 Jan, 2018 3.30.70.1440 Assigned
5ensD00 30 Nov, 2016 1.25.40.20 Assigned
5ensE00 30 Nov, 2016 1.25.40.20 Assigned
5ensF00 30 Nov, 2016 1.25.40.20 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB