PDB Information

PDB5ENR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli K-12
Primary Citation
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Sjuts, H., Vargiu, A.V., Kwasny, S.M., Nguyen, S.T., Kim, H.S., Ding, X., Ornik, A.R., Ruggerone, P., Bowlin, T.L., Nikaido, H., Pos, K.M., Opperman, T.J.
Proc.Natl.Acad.Sci.USA
HeaderTransport Protein
Released2015-11-09
Resolution2.300
CATH Insert Date17 Apr, 2016

PDB Images (25)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped
B 18 Apr, 2016 Chopped
C 18 Apr, 2016 Chopped
D 18 Apr, 2016 Chopped
E 18 Apr, 2016 Chopped
F 18 Apr, 2016 Chopped

CATH Domains (18)

Domain ID Date inserted into CATH Superfamily CATH Status
5enrA01 09 Jan, 2018 3.30.70.1430 Assigned
5enrA02 09 Jan, 2018 3.30.70.1320 Assigned
5enrA03 09 Jan, 2018 Holding pen
5enrA04 09 Jan, 2018 3.30.70.1430 Assigned
5enrA05 09 Jan, 2018 3.30.70.1440 Assigned
5enrB01 09 Jan, 2018 3.30.70.1430 Assigned
5enrB02 09 Jan, 2018 3.30.70.1320 Assigned
5enrB03 09 Jan, 2018 Holding pen
5enrB04 09 Jan, 2018 3.30.70.1430 Assigned
5enrB05 09 Jan, 2018 3.30.70.1440 Assigned
5enrC01 09 Jan, 2018 3.30.70.1430 Assigned
5enrC02 09 Jan, 2018 3.30.70.1320 Assigned
5enrC03 09 Jan, 2018 Holding pen
5enrC04 09 Jan, 2018 3.30.70.1430 Assigned
5enrC05 09 Jan, 2018 3.30.70.1440 Assigned
5enrD00 30 Nov, 2016 1.25.40.20 Assigned
5enrE00 30 Nov, 2016 1.25.40.20 Assigned
5enrF00 30 Nov, 2016 1.25.40.20 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB
P31224 ACRB_ECOLI Escherichia coli K-12 Multidrug efflux pump subunit AcrB