PDB 5em7

PDB Information

PDB5EM7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR.
Bryan, M.C., Burdick, D.J., Chan, B.K., Chen, Y., Clausen, S., Dotson, J., Eigenbrot, C., Elliott, R., Hanan, E.J., Heald, R., Jackson, P., La, H., Lainchbury, M., Malek, S., Mann, S.E., Purkey, H.E., Schaefer, G., Schmidt, S., Seward, E., Sideris, S., Wang, S., Yen, I., Yu, C., Heffron, T.P.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-11-05
Resolution2.810
CATH Insert Date10 Jan, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Jan, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5em7A01 16 Jan, 2016 3.30.200.20 Assigned
5em7A02 16 Jan, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor