PDB 5ei8

PDB Information

PDB5EI8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach.
Innocenti, P., Woodward, H.L., Solanki, S., Naud, S., Westwood, I.M., Cronin, N., Hayes, A., Roberts, J., Henley, A.T., Baker, R., Faisal, A., Mak, G.W., Box, G., Valenti, M., De Haven Brandon, A., O'Fee, L., Saville, H., Schmitt, J., Matijssen, B., Burke, R., van Montfort, R.L., Raynaud, F.I., Eccles, S.A., Linardopoulos, S., Blagg, J., Hoelder, S.
J.Med.Chem.
HeaderTransferase
Released2015-10-29
Resolution2.170
CATH Insert Date24 Apr, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ei8A01 08 May, 2016 3.30.200.20 Assigned
5ei8A02 08 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P33981 TTK_HUMAN Homo sapiens Dual specificity protein kinase TTK