PDB Information

PDB5E7R
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Structure-guided development of covalent TAK1 inhibitors.
Tan, L., Gurbani, D., Weisberg, E.L., Hunter, J.C., Li, L., Jones, D.S., Ficarro, S.B., Mowafy, S., Tam, C.P., Rao, S., Du, G., Griffin, J.D., Sorger, P.K., Marto, J.A., Westover, K.D., Gray, N.S.
Bioorg. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-10-13
Resolution2.110
CATH Insert Date09 Oct, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 10 Oct, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5e7rA01 13 Oct, 2016 3.30.200.20 Assigned
5e7rA02 13 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O43318 M3K7_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 7
Q15750 TAB1_HUMAN Homo sapiens TGF-beta-activated kinase 1 and MAP3K7-binding protein 1