PDB Information

PDB5E1S
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis.
Sanderson, M.P., Apgar, J., Garin-Chesa, P., Hofmann, M.H., Kessler, D., Quant, J., Savchenko, A., Schaaf, O., Treu, M., Tye, H., Zahn, S.K., Zoephel, A., Haaksma, E., Adolf, G.R., Kraut, N.
Mol.Cancer Ther.
HeaderTransferase
Released2015-09-30
Resolution2.260
CATH Insert Date25 Oct, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 Oct, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5e1sA01 01 Nov, 2015 3.30.200.20 Assigned
5e1sA02 01 Nov, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P06213 INSR_HUMAN Homo sapiens Insulin receptor
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