PDB 5dsx

PDB Links
Overview

PDB Information

PDB	5DSX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. Chen, C., Zhu, H., Stauffer, F., Caravatti, G., Vollmer, S., Machauer, R., Holzer, P., Mobitz, H., Scheufler, C., Klumpp, M., Tiedt, R., Beyer, K.S., Calkins, K., Guthy, D., Kiffe, M., Zhang, J., Gaul, C. Acs Med.Chem.Lett.
Header	Transferase
Released	2015-09-17
Resolution	2.410
CATH Insert Date	10 Jul, 2016

PDB Images (7)

Image of CATH 5dsx

5dsx

PDB 5dsx

Image of CATH 5dsxA

5dsxA

PDB Chain 5dsxA

Image of CATH 5dsxB

5dsxB

PDB Chain 5dsxB

Image of CATH 5dsxA01

5dsxA01

CATH Domain 5dsxA01

Image of CATH 5dsxA02

5dsxA02

CATH Domain 5dsxA02

Image of CATH 5dsxB01

5dsxB01

CATH Domain 5dsxB01

Image of CATH 5dsxB02

5dsxB02

CATH Domain 5dsxB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jul, 2016	Chopped
B	11 Jul, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dsxA01	14 Jul, 2016	1.10.260.60	Assigned
5dsxA02	14 Jul, 2016	3.40.50.150	Assigned
5dsxB01	14 Jul, 2016	1.10.260.60	Assigned
5dsxB02	14 Jul, 2016	3.40.50.150	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific