PDB 5dr2

PDB Information

PDB5DR2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2.
Janecek, M., Rossmann, M., Sharma, P., Emery, A., Huggins, D.J., Stockwell, S.R., Stokes, J.E., Tan, Y.S., Almeida, E.G., Hardwick, B., Narvaez, A.J., Hyvonen, M., Spring, D.R., McKenzie, G.J., Venkitaraman, A.R.
Sci Rep
HeaderTransferase
Released2015-09-15
Resolution2.460
CATH Insert Date24 Jul, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Jul, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5dr2A01 01 Sep, 2016 3.30.200.20 Assigned
5dr2A02 01 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
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