PDB 5dqc

PDB Information

PDB5DQC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design of Potent and Highly Selective Inhibitors for Human beta-Secretase 2 (Memapsin 1), a Target for Type 2 Diabetes.
Ghosh, A.K., Reddy, B.S., Yen, Y.C., Cardenas, E., Rao, K.V., Downs, D., Huang, X., Tang, J., Mesecar, A.D.
Chem Sci
HeaderHydrolase/Hydrolase Inhibitor
Released2015-09-14
Resolution2.470
CATH Insert Date10 Apr, 2016

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5dqcA01 07 May, 2016 2.40.70.10 Assigned
5dqcA02 07 May, 2016 2.40.70.10 Assigned
5dqcB01 07 May, 2016 2.40.70.10 Assigned
5dqcB02 07 May, 2016 2.40.70.10 Assigned
5dqcC01 07 May, 2016 2.40.70.10 Assigned
5dqcC02 07 May, 2016 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1